Stinkschoen schreef op 25 maart 2021 08:47:
Om nieuwe dag goed te starten een informatieve bijdrage. Rechtvaardigt mijn recente additionele aankoop (denkt mevrouw Stinkschoen hier ook zo over is de vraag die resteert).
Onderzoek (2021)
journals.lww.com/transplantjournal/Ab...Background: “ Background:
Complement activation in kidney transplantation is implicated in the pathogenesis of delayed graft function (DGF). This study evaluated the therapeutic efficacy of high-dose recombinant human C1 inhibitor (rhC1INH) to prevent DGF in a nonhuman primate model of kidney transplantation after brain death (BD) and prolonged cold ischemia.”
Conclusie:
Our results recommend high-dose C1INH complement-blockade in transplant recipients as an effective strategy to reduce kidney injury and inflammation, prevent DGF, delay AMR-development, and improve transplant outcomes