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fibrinogen on the move.

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  2. [verwijderd] 4 februari 2007 20:25

    • [verwijderd]

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    Hi Jurpsy de laatste 3 regels van jou vorige link is daarover inmiddels almeer bekend qua onderzoek uit Japan?

    Citaat; Current corporate collaborations include an agreement with Taisho Pharmaceutical Co. Ltd. of Japan to develop novel therapeutics to prevent scarring and eventual loss of kidney function, a leading cause of death among patients with diabetes.
  3. [verwijderd] 4 februari 2007 22:03

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    Jurpsy,

    i.e. lijst van de universiteit van Californie, research administration office, over welke natuurlijke of rechtspersonen de opleiding iets toestoppen. Zijn er samnewerkingsverbanden met UCOP?
    groet
    N.
  4. jurpsy 14 februari 2007 20:40

    • jurpsy

      Lid sinds: 22 nov 2004

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    nihildabo,

    onder het motto beter laat dan nooit..waarvoor mijn excuses.

    In de jaren 90 moet er wel samenwerking zijn geweest tussen beide partijen.Of toch beide dezelfde interesse...
    Hoe het momenteel zit heb ik geen idee , wellicht anderen hier????

    mvg , jurpsy
  5. jurpsy 15 april 2007 05:13

    • jurpsy

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    Fibrin bandages
    Wednesday 31 January 2007 @ 7:09 pm
    With ongoing conflicts in Iraq, Afghanistan, and recently in Somalia, the men and women of our armed forces continue to be in harm’s way. From first-responder care in the battlefield, to rapid evacuation to advanced care hospitals, and finally to rehabilitation centers in the United States, the medical care injured soldiers receive is top-notch.

    The most challenging of aspect of combat injuries and trauma injuries in general is getting the patient from the battlefield or car accident to an advanced care hospital. This transit time is often called the “Golden Hour”. While studies of trauma medicine show there is nothing significant about the 60 minute window, the point is that time is an essential to surviving a traumatic injury.

    Unfortunately, rapid transit sometimes isn’t enough to help heavily-bleeding wounds from bullets and shrapnel from I.E.Ds. (improvised explosive devices). New advances in bandage technology are going a long way to preventing heavy blood loss and saving the lives of soldiers who otherwise might die on the evacuation helicopter or even before the helicopter arrives.

    After the 9/11 attacks, FDA testing was fast-tracked for bandages containing fibrinogen and thrombin, two proteins necessary to cause blood coagulation (clotting). [1] Fibrin is the stuff that makes up the scabs that protect the underlying skin while it regenerates.

    So, how does blood clot?
    I’ll spare you the complex details as the whole process involves a complex cascade of 28 components, but the general outline is this: Upon injury, platelet cell in the nearby bloodstream immediately start to stick together and do their best to form a plug at the site of blood loss. This process of sticking together, primary haemostasis (some Latin for you: haemo - blood, stasis - stop), is caused by the platelet being activated by injured collagen, a protein component of skin. Secondary haemostasis works to reenforce the platelet plug by forming fibrin strands that crosslink to form a very protective shield over injured tissues. [2]

    In serious injuries, the blood flow overwhelms the speed of the clotting cascade (i.e. platelet cells get flushed into the cloth gauze being applied to injury) and it’s difficult/impossible for the body to form cross-linking fibrin to stop the bleeding. What these high-tech bandages do is accelerate the sophisticated coagulation cascade because they contain some of last steps of the cascade (fibrinogen and thrombin) and help stop bleeding as soon as possible. This allows the combat medic to do more in the field and save lives.

    —–
    While fibrin bandages are a great advancement for our armed forces, there are many other ways we all can do to support those who have, currently are, or will be deployed.
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