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***** GTCB 2007 ******

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  13. [verwijderd] 5 september 2007 08:16

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    Possible / Probable News Flow

    [Added item #3 on submission
    and acceptance of ATryn BLA.]

    1. A partnership for ATryn in the US. This is apt to be the most consequential news item of the next 12 months. It could come at any time (#msg-21999558).

    2. A partnership for ATryn in Japan. Japan has substantial sales of plasma-derived antithrombin, including an approved indication for DIC/sepsis. These plasma-derived sales represent low-hanging fruit for eventual conversion to ATryn. At least one Japanese clinical study (by a GTC partner) will be needed to obtain marketing approval.

    3. Submission and acceptance of the ATryn BLA for review. Submission is expected toward the end of 1Q08 and acceptance of the BLA for review occurs approximately 60 says after submission. The relevance of the acceptance-for-review date is that the FDA decides whether to conduct a Priority Review at that time. (Priority Review shortens the review time from 10 months to 6 months.)

    4. A new supply deal similar to the one with Merrimack. The effect of such an announcement on the stock price could be large, depending of course on the partner and the partnered drug.

    5. A development partner for the CD137 program. This would be significant because CD137 is the most advanced internal program that is not based on a plasma protein.

    6. Something out of the blue. With a company such as GTC that has so many possibilities, it’s not unreasonable to expect the unexpected.

  15. [verwijderd] 5 september 2007 15:20

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    Pre-Market
    Last: $ 1.21 Pre-Market
    High: $ 1.21
    Pre-Market
    Volume: 8,300 Pre-Market
    Low: $ 1.15


    Pre-Market
    Time (ET) Pre-Market
    Price Pre-Market
    Share Volume
    09:12 $ 1.21 100
    09:12 $ 1.21 900
    09:09 $ 1.19 1,100
    09:09 $ 1.20 100
    09:09 $ 1.20 100
    09:09 $ 1.20 800
    09:09 $ 1.20 100
    09:09 $ 1.20 900
    09:09 $ 1.20 100
    09:09 $ 1.20 100
    08:59 $ 1.16 1,500
    08:31 $ 1.15 2,500

2.783 Posts
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Forum # Topics # Posts
Aalberts 466 7.017
AB InBev 2 5.496
Abionyx Pharma 2 29
Ablynx 43 13.356
ABN AMRO 1.582 51.650
ABO-Group 1 22
Acacia Pharma 9 24.692
Accell Group 151 4.132
Accentis 2 264
Accsys Technologies 23 10.645
ACCSYS TECHNOLOGIES PLC 218 11.686
Ackermans & van Haaren 1 188
ADMA Biologics 1 34
Adomos 1 126
AdUX 2 457
Adyen 14 17.751
Aedifica 3 916
Aegon 3.258 322.830
AFC Ajax 538 7.088
Affimed NV 2 6.296
ageas 5.844 109.892
Agfa-Gevaert 14 2.050
Ahold 3.538 74.335
Air France - KLM 1.025 35.043
AIRBUS 1 12
Airspray 511 1.258
Akka Technologies 1 18
AkzoNobel 467 13.036
Alfen 16 24.806
Allfunds Group 4 1.473
Almunda Professionals (vh Novisource) 651 4.251
Alpha Pro Tech 1 17
Alphabet Inc. 1 406
Altice 106 51.198
Alumexx ((Voorheen Phelix (voorheen Inverko)) 8.486 114.822
AM 228 684
Amarin Corporation 1 133
Amerikaanse aandelen 3.837 243.177
AMG 971 133.329
AMS 3 73
Amsterdam Commodities 305 6.689
AMT Holding 199 7.047
Anavex Life Sciences Corp 2 491
Antonov 22.632 153.605
Aperam 92 14.998
Apollo Alternative Assets 1 17
Apple 5 381
Arcadis 252 8.776
Arcelor Mittal 2.033 320.706
Archos 1 1
Arcona Property Fund 1 286
arGEN-X 17 10.300
Aroundtown SA 1 219
Arrowhead Research 5 9.737
Ascencio 1 27
ASIT biotech 2 697
ASMI 4.108 39.096
ASML 1.766 107.176
ASR Nederland 21 4.485
ATAI Life Sciences 1 7
Atenor Group 1 491
Athlon Group 121 176
Atrium European Real Estate 2 199
Auplata 1 55
Avantium 32 13.667
Axsome Therapeutics 1 177
Azelis Group 1 64
Azerion 7 3.392

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